Is there a better "Big Bang" duo than Sheldon and Penny? They never dated, but Sheldon and Penny’s friendship is one of the most important relationships of the entire series.
A lot of bad things happend to Sheldon on "The Big Bang Theory." For this list, we’ll be looking at the times the others pushed Sheldon’s buttons (deservingly atau not) so much that we actually felt sorry for him.
![Sheldon Cooper :]](http://images5.fanpop.com/image/photos/24600000/Sheldon-Cooper-sheldon-cooper-24678236-500-400.jpg)