normally i would say peyton but she was 'done' after season 6 and brookes life is still going and some serious shit has happened to her in the past 2 season .. and even in season 6 she's been through hell,while peyton was MOSTLY happy.

Both of Peytons moms died, and everybody in her life left her except lucas. Hand down. brooke didnt have that hard of a life. yeah heer parents didnt want her,and lucas cheated but it dosen compare to peytons.

I'm just asking, becaus like Jessica4695 said usually hands down the answer would be Peyton without a doubt, but now that Peytons gone I think Marks started making all the bad things happen to Brooke. I however, still believe Peyton had the harder life because she lost TWO moms, got attacked by a psycho twice, got shot in the leg, lost multiple loved ones, her dad was never around, got accused of being a lesbian then had a horrible rumor spread around, lost her bestfriend twice, almost died giving birth, got into a car crash while she was pregnent, and I'm pretty sure there is something I'm missing.
But up next would deffinetly be Brooke. I think she had a pretty easy highschool life, but the last two seasons all the bad things seem to be happening to her.Brooke had no parental supervision her whole life and her parents basically ignored her, lost her first highschool love to her bestfriend, lost her bestfriend a couple of times, got attacked, almost drowned, found out she couldn't have kids,lost her comany like twice, and once again I'm pretty sure there is more.

TWO mothers dead, two times attacked by stalker, lost her love of her life couple of times also almost lose him after two accidents that he had, didnt see her dad so often..like never!!!, lost Jake who she cared about....had a very very difficult pregnancy, was shot in the leg, had a car crash.... well i think that sums it up that she HANDS DOWN has had the worst life ever!!!

Without question.

definatly her.

No doubt

1- Peyton - without a doubt

then


2- Brooke
3/4- Lucas / Nathan
5- Haley

Of course.