Nathan and Peter face off, and Nathan makes a pindah with devastating consequences. Sylar takes desperate measures at Primatech and the fates of several heroes hang in the balance. Ando, Matt, and Daphne continue their quest to save Hiro.
Matt finds out the identity of the person who shot Nathan, Sylar looks for Claire to help bring back his lost abilities and Hiro learns about the dark secret of the Nakamura family that could have dire consequences on the world.